Interventional Radiology

General Information

Dear Patients,

On the following pages we have tried to summarised the relevant informations for you about Trans-Arterial percutaneous Chemo-Embolisation.

There are various forms of curative therapy available for the treatment of liver tumors. Among these are methods like Laser- Induced Thermotherapy (LITT) which is regularly performed at our institution, and other special local treatment methods ( e.g., alcohol instillation) in addition to surgical resection. Various systemic medications (chemotherapy) are used along with these procedures. "Transarterial Chemoembolization (TACE)" which is performed on a regular basis at our institution shows promising results in the treatment of liver metastases. The choice of therapy, combination of different medications and also the time of starting the therapy have not been standardized and are adapted to the individual patient requirements. In TACE, the knowledge of difference in blood supply to the tumor and liver tissue is used. Up to 75% of the normal liver tissue is perfused by the portal venous system and only 25% is supplied by arteries. On the contrary, liver tumors are supplied up to 95% by arteries. Hence chemoembolization of liver arteries lead to development of ischemic necrosis in the tumor region while the remaining normal liver tissue is spared by sufficient perfusion through the portal venous system.

Above all, application of chemotherapy through the major arteries into the liver arteries allows one to achieve a concentration 100 times higher than by systemic approach with only minimal adverse effects. The half-life of chemotherapeutic agent is increased by hours to weeks through the stoppage of blood supply.

Indications for Trans-Arterial Chemo-Embolization:

Indications for Transarterial Chemoembolisation:

  • Unresectable (surgically or by laser induced thermotherapy) liver metastases and primary Livertumors diagnosed intraoperatively or morphologically using CT and MRI examinations.
  • Not responding to systemic chemotherapy.

Criteria for transarterial chemoembolization:

Pre-conditions for Trans-Arterial Chemo-Embolisation:

  • Normal liver vessel architecture with good perfusion of both liver lobes.
  • Patent portal vein.
  • No ascites.
  • Good liver function.
  • Good general condition of the patient.

Advantages of Trans-Arterial Chemoembolization:

  • Associated with very little stress for the patient
  • Complication-free Procedure with good quality of life
  • Relatively shortened hospital stay (done on an outpatient basis)
  • Reduction of tumour growth or reduction in tumour size

A female patient with liver metastases of ovarial carcinoma.

Patient with hepatocellular carcinoma (HCC).


The CT image taken after 24 hours of intervention shows a good emplacement of the chemoembolisat.



Make your examination appointment Monday through Friday between the hours of 07:30 and 17:00.

Secretariat Prof. Thomas J. Vogl

 069 6301-7277

Intervention Clinic

 069 6301-4736

Central Radiology

 069 6301-87202

Gynaecological radiology

 069 6301-5174

Paediatric radiology

 069 6301-5248

Orthopaedic radiology

 069 6301-94211

069 6301-​87202