Interventional Radiology

Laser-induced Interstitial Thermotherapy (LITT)

Dear Patients,

on this page we would like to inform you about the minimum invasive therapeutic procedures offered at our institute.


The use of local thermal effect in the tumor region forms the basis for this new minimal- invasive therapeutic procedure. Since the development of MRI-guided laser-induced Interstitial ThermoTherapy (LITT), it is possible to target the laser exactly on the tissue volume to be treated. Due to comparably high penetrability of photons and the possibility of complication-free transfer of energy through guide-light, Laser of Near Infrared Region (NIR) is used for LITT. Above all we use the Nd:YAG-Laser (1,064 nm), which has a wide clinical use.


The energy is applied to the target tissue using special laser applicators. The energy of laser light is absorbed, which causes heating of the tissue. The heat causes coagulation (destruction) of tumor tissue and the edge around it. In order to make the advantages of the effect and accuracy of the therapy useful, all the factors contributing to the success of therapy must co-ordinate with one another. For this, it is necessary to calculate the exact duration and output of the laser. Therefore under certain circumstances more laser applicators and more cycles of therapy, may be required depending on size, number and location of the lesion to be treated. These parameters are adapted individually according to the illness. In practice a temperature of about 60 to 110° C is achieved in the tumor tissue. This differentiates LITT from the classical hyperthermia.
It is scientifically proven that local resection or destruction of liver metastases prolongs the life of patients.

Effects of LITT

Metastasis in segment 8, non-enhanced MRI before LITT


Metastasis in segment 8, contrast-enhanced MRI before LITT


Metastasis in segment 8, non-enhanced MRI after LITT. The metastasis and the edge around is fully coagulated.


Metastasis in segment 8, contrast-enhanced MRI after LITT

For whom is this therapy suitable?

1. LITT of liver tumours

  • Maximum number: 5 lesions
  • Maximum diameter: 50 mm
  • Residual metastases in patients who have already undergone liver resection.
  • Progress of metastases despite chemotherapy
  • Bilobar metastases (involvement of both lobes of liver)
  • Patients who are contraindicated for operation
  • Patients who are primarily inoperable can be brought to an operable situation with LITT (metastases in both liver lobes)
  • LITT as alternative therapy for patients who refuse surgical resection and systemic or local chemotherapy
2. LITT of lung metastases and lung tumors
3. LITT of soft tissue tumors
  • Residual tumors
  • Head and neck region
  • Upper abdomen
  • Retroperitoneum
  • Lymph node metastases
  • Head and neck region
  • Upper abdomen
  • Retroperitoneum


Vereinbaren Sie Ihren Untersuchungstermin von Montag bis Freitag in der Zeit von 07:30 bis 17:00 Uhr.

Sekretariat Prof. Thomas J. Vogl

 069 6301-7277


 069 6301-4736


 069 6301-87202

Gynäkologische Radiologie

 069 6301-5174


 069 6301-5248

Orthopädische Radiologie

 069 6705-​211

069 6301-​87202